With this in mind, essential oils are safe to use, and the higher the quality, the safer and more effective they will be. LD50 acute, rats, dermal, >2000 mg/kg LD50 acute, dogs, dermal, >5000 mg/kg Etofenprox is less irritant than most pyrethroid esters (e.g. Nessa. Merial/Boehringer Ingelheim. In sharp contrast, anti-flea products generally considered safe for cats contain less than 0.1% of … One guinea-pig was given [5-14 C]racemic methoprene (purity, 96.9%) at a single dose of 49 mg/kg bw by gavage, and urine, faeces and expired CO 2 were collected for 24 h.At that time, the animal was killed, and samples of blood, fat and muscle were taken. The active ingredients in Frontline Plus for dogs consist of 9.8% of Fipronil and 8.8% of S-methoprene. All PetFriendly products are EPA-approved safe and effective, featuring the same vet-quality ingredients, at 20-40% less than the Big Brands. Socha R et al (1990) Comments on safety of methoprene. Hartz UltraGuard Plus Flea & Tick Treatment for Cats & Kittens over 5 lbs is a topical, monthly treatment that kills fleas, flea eggs, deer ticks and repels mosquitoes. Methoprene is also metabolized rapidly in soil and does not leach29. This effective formula stops the flea life cycle and prevents re-infestation for up to 30 days. Frontline for Cats also has a secondary ingredient, called (S)-methoprene, which is a juvenile insect hormone that acts as a regulator, killing eggs and larvae to stop the next generation of pests from reaching adulthood. Elanco The North American Essential Oil and Aromatherapy Experts has explored essential oils safe for cats, as well as many veterinarians and pet wellness explorers. The active ingredients listed on the front of the packaging on both boxes provide different amounts for the (S)-methoprene ingredient; 11.8% for cats and 8.8% for dogs from 23-44 lbs. Harvey R G et al (1997) Prospective study comparing fipronil with dichlorvos/fenitrothion and methoprene/pyrethrins in control of flea bite hypersensitivity in cats. Known as a juvenile hormone analog, S-methoprene mimics an insect’s hormones and prevents fleas from producing eggs of their own. Yes. It also contains fipronil and (S)-Methoprene, which are the same active ingredients as Frontline Plus for cats. There is a major difference between Frontline Plus for dogs and Frontline Plus for cats despite the fact that its ingredients Fipronil and S-methoprene are approved to use on both cats and dogs. Suitable to use on cats over 8 weeks of age. Juvenile growth hormone mimics, such as methoprene, fenoxycarb, and pyriproxyfen, interfere with insect maturation and prevent the insect from reaching the adult stage. Permethrin poisoning is still one of the most common poisonings of cats worldwide and it can be life-threatening. >2000 mg/kg. Guinea-pigs. 1 decade ago. Yes. Frontline Plus is safe to use for cats and kittens 8 weeks and older. Several pet owners are of the opinion that it’s safe and economical to use frontline for dogs on cats but this isn’t true. Unfortunately, even indoor cats aren’t safe from the bloodsuckers. Products containing (S)-methoprene and Pyriproxyfen are known as Insect Growth Regulators (IGRs) and help control flea populations by sterilizing eggs for up to 4 – 7 months after application. When s-methoprene enters the body it is broken down quickly and then excreted, though it can be stored in the body in very small amounts. These are not safe for cats. Inert ingredients for dogs are 81.4%. However, it is known to be safe to a wide variety of animals unless a particularly large dose (10g/kg) is ingested. But the majority of over-the-counter flea collars rely on chemical compounds that can be toxic for cats. It contains two powerful compounds – insecticide and insect growth regular components. This curbs the growth of the infestation. It includes a three-month supply and you can apply flea drops once every 30 days. Methoprene interferes with an insect's normal maturation process, preventing larvae to mature to reproductive adult stages. The product is for external use only. Fipronil, methoprene, and cyphenothrin is not for use on cats. 0 0. TevraPet's flea prevention for cats has 2,442 ratings on Amazon and an average of four out of five stars. Manufacturer. I have the original packaging for the last supply of Frontline for both animals which had the single dose applicators. Thus, Methoprene is not expected to persist in soil or contaminate ground water. It contains two powerful compounds – insecticide and insect growth regular components. Virbac Knockout E.S. Advantix is 50% permethrin. Can be used on 4 weeks and older kittens. Thus, as you can see, both the Frontline products have the exact same Fipronil content, but the difference lies in the percentage of the ingredient S-Methoprene. Flea & Tick Treatments Plus Flea and Tick Treatment for Cats. While for cats, Frontline Plus contains 9.8% Fipronil and 11.8% S-methoprene. Nitenpyram. Capstar is the best oral flea treatment for cats whose active ingredient is the Nitenpyram. Fipronil – a strong insecticide kills fleas and ticks without causing any harm to cats. However, it is known to be safe to a wide variety of animals unless a particularly large dose (10g/kg) is ingested. CENTRAGARD ™ (eprinomectin and praziquantel transdermal solution), innovative internal parasite protection for cats, launched in the U.S.. Heartworm disease is a serious and potentially deadly threat to cats. An example of this class of IGR is methoprene (Figure 6.1), which was first registered and marketed in 1975 (Henrick, 2007). Even worse is the fact that loving owners can accidentally poison their cats by using dog flea spot-on products containing permethrin because they do not recognise the dangers. Overview of Fipronil and Methoprene (Frontline Plus®) for Dogs and Cats Fipronil and methoprene, commonly known as Frontline Plus®, is used in the control and treatment of all stages of flea infestations and tick infestations in dogs and cats Fipronil is a phenylpyrazole antiparasitic agent and methoprene is an insect growth regulator. Frontline for dogs contains two active ingredients namely fipronil and s-methoprene in certain amounts. People can suffer mild irritation if it enters their system via the skin or lungs. Frontline Plus for cats is the most popular flea and tick preventive for cats. Humans can suffer mild irritation if s-methoprene enters their system via the skin or lungs. The same ingredients are present in the cat formula but in varying amounts. There are flea collars that are composed of a natural base and safe approach that poses little risk of serious side effects to your cat. Is methoprene safe for cats keyword after analyzing the system lists the list of keywords related and the list of websites with related content, in addition you can see which keywords most interested customers on the this website The spot treatment can cause violent reactions in your pets, and I have a close friend that just had a bad experience with this a few months ago. Fipronil, (s)-methoprene. Usually, the onset of action is 30 minutes, and its effect lasts for 48 hours upon which most adult fleas would have died. This will most probably be the fipronil’s effect as the (S)-methoprene is considered safe. Frontline Plus for cats is the most popular flea and tick preventive for cats. Source(s): hartz spot treatment cats safe ingredient methoprene: https://biturl.im/1ue6t. Inert ingredients for dogs are 81.4%. Is it safe for pregnant and lactating cats? The (S)-methoprene is also effective in preventing the development of larvae and pupae chip, prevents contamination of the habitat of cats treated with the immature stages of fleas. Is It Safe? They usually contain permethrin, an insecticide commonly found in low concentrations in some canine and feline flea sprays and shampoos. So here’s the moment of truth, are flea collars safe for cats? While Frontline Plus for dogs has 9.8% of Fipronil content and 8.8% of S-methoprene content, Frontline Plus for cats has 9.8% of Fipronil, but 11.8% of S-Methoprene. How does my indoor cat conduct parasites? The active ingredients in Frontline Plus for dogs consist of 9.8% of Fipronil and 8.8% of S-methoprene. Ingredients. However, cats are one notable exception as they won’t be able to metabolize permethrin. Smith C A (1995) Searching for safe methods of flea control. PLEASE do not use anything from Hartz, including their shampoo. Fipronil - 9.8% (s)-methoprene - 11.8% Target pests : Fleas and Ticks For use in : Cats (over 8 weeks old) Application : One (1) pipette of 0.5 ml per cat (up to 8 kg) Pet safe … JAVMA 206(8) 1137-1143. When s-methoprene enters the body it is broken down quickly and then excreted, though it can be stored in the body in very small amounts. Frontline Plus has a rapid onset of action and kills re-infestations with newly acquired adult fleas for at least 1 month, and also prevents the development of flea eggs, larvae and pupae produced by any adult fleas acquired for up to 3 months after treatment. Frontline Plus for cats is a topical 'spot-on' application for flea treatment on cats and kittens. When exposed to it, cats could even die after a few days. Toxicity concerns from overexposure or ingestion of current topical spot-on products come primarily from the adulticidal component of the product rather than methoprene. Ecological effects Methoprene has been shown to be practically non-toxic to terrestrial species including mallard ducks31 and quail32 and Methoprene had no effect on mallard33 or quail34 reproduction. The ingredient works very fast killing fleas in cats within six hours while those in dogs die in four hours’ time. Caution is needed when using on pregnant, nursing, debilitated, aged, or sensitive dogs. Use only on cats or kittens over 5 pounds, 12 weeks of age and older. cyphenothrin, phenothrin, permethrin, etc.). LD50 acute, rats, p.o. Permethrin acts as a nerve toxin. Other uses include crop and home pest control and oral and topical flea control in dogs and cats. Fipronil – a strong insecticide kills fleas and ticks without causing any harm to cats. This should not be dangerous, but you’re still urged to take your pet to the vet for a check-up. cats despite the fact that its ingredients Fipronil and S-methoprene are approved to use on both cats and dogs. Heartworms are difficult to diagnose in cats, and there is no approved treatment to eliminate feline heartworm infections. Frontline Plus is safe to use for cats and kittens 8 weeks and older. Our Paws Plus® for Cats topical product is produced in USA and Germany, and contains the same active ingredients as in Boehringer Ingelheim’s Frontline Plus(r) for Cats: Fipronil & s-Methoprene. a Average for two animals. Vet Parasitol 141(24) 628-629. This topical flea treatment by PetArmor kills existing ticks and fleas in all life stages and works for up to 30 days on eliminating reinfestation.. Comparative Efficacy of Imidacloprid, Selamectin, Fipronil-(S)-Methoprene, and Metaflumizone against Cats Experimentally Infested with Ctenocephalides felis Season-long control of flea and tick infestations in a population of cats in the Aeolian archipelago using a collar containing 10% imidacloprid and 4.5% flumethrin There is limited published information detailing adverse effects of methoprene in dogs or cats; however, given the mechanism of action, clinical effects are expected to be mild. Which had the single dose applicators from hartz, including their shampoo flea & tick Treatments Plus flea tick. Flea treatment on cats over 8 weeks of age and older, permethrin etc! Heartworm infections poisonings of cats worldwide and it can be used on 4 weeks and kittens! Known to be safe to use on cats and kittens 8 weeks of age or under 4.. 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